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GLP-1: a new therapeutic class of major interest

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According to the 244-page master complaint, both drug manufacturers did not disclose the gastrointestinal and other health risks associated with taking glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the drug class to which these medications belong

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The first ADC for treatment of solid tumors was Ado-Trastuzumab Emtansine (Kadcyla ) or T-DM1 for treatment of HER2+ metastatic or locally advanced breast cancer and was approved in 2013 (162)

Why does tolerability matter more than peak efficacy